The Louisiana Department of Health reported an additional 582 COVID-19 cases and 21 deaths Wednesday.
The running totals of each since the pandemic began stood at 431,771 cases and 9,668 deaths.
Hospitalizations fell by 41 to 588 with 78 patients on ventilators, 11 fewer than Tuesday.
LDH also updated the number of presumed recovered from the coronavirus to 415,954, an increase of 7,491 since last week.